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Alzheimer’s disease and other forms of dementia impact millions of lives around the world. Raising awareness, promoting brain health, and providing support to those affected are essential steps toward building an inclusive, informed society.

What is Alzheimer’s Disease ?

Alzheimer’s is the most common cause of dementia, marked by brain cell damage due to amyloid plaques, tau tangles, and progressive shrinkage of the brain. Symptoms often begin with mild memory lapses and gradually escalate to loss of independence and full-time care needs.

Important Facts to Know:

  • Over 55 million people live with dementia globally.
  • In India, nearly 8.8 million individuals are estimated to be living with dementia.
  • 1 in 9 people aged 55 and above is affected by Alzheimer’s.
  • Early symptoms include memory loss, confusion, difficulty with familiar tasks, and mood changes.

    • Tips for Maintaining Brain Health:

    • While there is no known cure, lifestyle changes can help reduce risk and promote mental wellness:

      1. Keep Mentally Engaged
         Read, solve puzzles, learn new skills—keep your brain challenged.

      2. Stay Physically Active
         Regular exercise boosts blood flow to the brain and overall well-being.

      3. Eat a Brain-Friendly Diet
         Prioritize fruits, vegetables, nuts, whole grains, and healthy fats.

      4. Get Quality Sleep
         Good sleep is critical for memory consolidation and brain repair.

      5. Stay Socially Connected
         Isolation can accelerate cognitive decline—stay engaged with others.

      6. Manage Health Conditions
         Conditions like hypertension and diabetes can increase risk; regular check-ups help.

      Protect Your Brain
       Avoid injuries by using helmets, securing your environment, and managing fall risks.

    How You Can Support:

  • Start Conversations about brain health and dementia to break stigma.
  • Show Compassion for individuals and families living with dementia.
  • Volunteer, Donate, or Advocate for individuals and families living with dementia.
  • Educate Yourself and Others, awareness empowers action.

    • Blood Tests for Earlier, Easier Diagnosis

      • FDA-approved tests now detect amyloid and tau with up to 90% accuracy in symptomatic individuals aged 55+. 
      • UK NHS trials are testing diagnostic blood tests with 3,000+ participants to roll out accessible, low-cost diagnosis across the country. 
      Impact: Diagnosis is becoming faster, less invasive, and more scalable.

    New Tools for Risk Assessment & Monitoring

    • DuAL-Net, an AI tool, uses whole-genome sequencing to accurately predict Alzheimer’s risk.
    • Finger-movement analysis is emerging as a low-cost, non-invasive early detection method.

    Digital neuromodulation (Spectris AD™) has shown promise in slowing cognitive decline and preserving brain volume.

    MIND Diet Proven to Cut Dementia Risk

    Recent studies show that even mid-life adoption of the MIND diet can reduce dementia risk by up to 25%. Key foods:

    • Leafy greens, berries, nuts
    • Whole grains, olive oil, beans
    • Fish, poultry, limited red meat/sweets

    • Even late starters can see measurable benefits in brain health.

    Wider Research Shifts Beyond Amyloid

    • MIT research is identifying DNA repair and RNA modification pathways as alternative targets for therapy.

       

    A new mutation atlas is helping scientists understand how over 140,000 mutations affect amyloid formation.

    With advances in blood-based diagnostics, AI-driven risk assessment, preventive diet plans, and novel therapies, we are moving closer to a future where Alzheimer’s is detected earlier, treated more effectively, and one day prevented altogether.

    Note: As June is considered the Alzheimer’s & Brain Awareness Month, wear purple, participate in awareness events, and share knowledge that can help reduce stigma and promote early action.